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Carotenoids and vitamin A

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By: Sean Moloughney

Editor, Nutraceuticals World

Indication: Polyps

Source: Intl J Cancer, November 2004;112(2):295-305.

Research: A study examining 843 subjects undergoing low fat, high fiber, high fruit and high vegetable dietary intervention revealed information related to polyp recurrence. During the study researches monitored polyp recurrence and carotenoid and vitamin A values after adjustment for covariates.

Results: The risk of adenomatous polyp recurrence was inversely related to alpha-carotene concentrations and right-sided polyps; alpha-carotene intake and recurrence of any, multiple and right-sided polyps; beta-carotene intake and multiple adenoma recurrence; and vitamin A from food and dietary supplements and each adverse endpoint. The researchers concluded alpha-carotene and vitamin A may protect against adenomatous polyp recurrence in nonsmokers and nondrinkers or be indicative of compliance or another healthy lifestyle factor that reduces risk.

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